Round 7: Tossup 17
In an unknown mechanism, the release of this compound is induced by berdazimer sodium during treatment for water warts. High eosinophil (“ee-oh-SIH-noh-fil”) count and elevated fractional exhaled levels of this compound are often observed in patients with asthma caused by type 2 inflammation. Drugs that [emphasize] promote the action of this compound function by inhibiting the type 5 isoform of phosphodiesterase (“FOS-foh-dye-ESS-ter-ayz”), thereby inducing the relaxation of the corpus (*) cavernosum. A group of synthases with neuronal, inducible, and endothelial isoforms generate this compound from the oxidation of arginine to citrulline. By preventing cGMP degradation, the drug sildenafil enhances the effects of this compound to treat erectile dysfunction. For 10 points, name this gaseous signaling molecule, a potent vasodilator consisting of one oxygen and nitrogen atom. ■END■
ANSWER: nitric oxide [or NO or nitrogen monoxide until “nitrogen” is read; accept fractional exhaled nitric oxide or FENO; accept nitric oxide synthase; reject “nitrous oxide” or “N2O” or “dinitrogen oxide” or “nos”]
<KN, Biology> | NAFTA-Packet-7
= Average correct buzzpoint
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