Packet 7: Tossup 17

In an unknown mechanism, the release of this compound is induced by berdazimer sodium during treatment for water warts. High eosinophil (“ee-oh-SIH-noh-fil”) count and elevated fractional exhaled levels of this compound are often observed in patients with asthma caused by type 2 inflammation. Drugs that [emphasize] promote the action of this compound function by inhibiting the type (15[1])5 isoform of phosphodiesterase (15[1]-5[1])(“FOS-foh-dye-ESS-ter-ayz”), thereby inducing (15[1])the relaxation of the corpus (*) cavernosum. (10[1])A group of (10[1])synthases (10[2])with (10[1]-5[1])neuronal, (10[1])inducible, and (10[2])endothelial isoforms generate (10[1])this compound from the oxidation (10[1])of arginine to citrulline. (10[2]-5[2])By preventing (10[2])cGMP degradation, the drug sildenafil enhances the effects (10[1]-5[1])of this compound (10[2])to treat erectile dysfunction. (10[4]-5[1])For 10 points, (10[1])name this gaseous signaling (10[1])molecule, (10[2])a potent vasodilator consisting of one oxygen and nitrogen atom. ■END■ (10[5]0[7])

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