Round 7: Tossup 17

In an unknown mechanism, the release of this compound is induced by berdazimer sodium during treatment for water warts. High eosinophil (“ee-oh-SIH-noh-fil”) count and elevated fractional exhaled levels of this compound are often observed in patients with asthma caused by type 2 inflammation. Drugs that [emphasize] promote the action of this compound function by inhibiting the type 5 isoform of phosphodiesterase (“FOS-foh-dye-ESS-ter-ayz”), thereby inducing the relaxation of the corpus (*) cavernosum. A group of synthases with neuronal, (10[1])inducible, and endothelial isoforms generate this compound from the oxidation of arginine to citrulline. (10[1])By preventing cGMP degradation, the drug sildenafil enhances the effects of this compound to treat erectile dysfunction. For 10 points, name this gaseous signaling molecule, a potent vasodilator consisting of one oxygen and nitrogen atom. ■END■

ANSWER: nitric oxide [or NO or nitrogen monoxide until “nitrogen” is read; accept fractional exhaled nitric oxide or FENO; accept nitric oxide synthase; reject “nitrous oxide” or “N2O” or “dinitrogen oxide” or “nos”]
<KN, Biology> | NAFTA-Packet-7
= Average correct buzzpoint

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