Round 3: Tossup 13

An oxide of this element can be used alongside A·T·R·A to degrade P·M·L/R·A·R·A in sufferers of acute promyelocytic (“proh-MY-loh-SIH-tick”) leukemia. Another form of this element binds to the vicinal (“VISS-ih-null”) di·thiol of the lipoic acid cofactor of pyruvate dehydrogenase to inhibit the enzyme’s activity. (15[1])Inorganic forms of this element are methylated into M·M·A and D·M·A in the liver. This element bonds to 2-amino·phenol to form an antimicrobial first used to kill off (*) Treponema pallidum. (10[1])This is the heaviest element found in Salvarsan, a drug developed by (10[1])Paul Ehrlich’s lab to treat syphilis. In its main mode of toxicity, this pnictogen’s oxyanion replaces phosphate during glycolysis to inhibit ATP (10[1])synthesis. For 10 points, name this toxic group 15 metalloid whose trioxide was once used as rat poison. ■END■ (10[1])

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