Packet 8: Bonus 4
Improper loading of protein samples during this technique may lead to the resolution of “leopard skin” patterns. For 10 points each:
[10m] Name this technique whose “single-particle” variant aligns homogenous samples using cross-correlation. Dubochet, Frank, and Henderson were awarded a Nobel Prize in 2017 for developing this technique.
ANSWER: cryo-EM [or cryo-electron microscopy or electron cryomicroscopy or cryo-TEM or ECT or electron cryo-tomography or cryo-electron tomography or cryo-ET or CET; prompt on scanning electron microscopy or transmission electron microscopy; prompt on microscopy]
[10h] In 2020, this protein’s structure was reconstructed at a 1.22 angstrom resolution using single-particle cryo-EM. Proteins named for resembling this hollow 24-subunit protein can be encased by family 1 encapsulins.
ANSWER: ferritin [or apoferritin; accept bacterioferritin; accept ferritin-like proteins; prompt on FLPs]
[10e] Since 2022, single-particle cryo-EM has been used to assess the viability of ferritin-based D·C·F·H·P vaccines targeting this pathogen with delta and omicron variants.
ANSWER: COVID-19 virus [or SARS-CoV-2 or severe acute respiratory syndrome coronavirus 2; accept coronavirus disease 2019; prompt on SARS-CoV or coronavirus or covid]
<MS, Biology> | NAFTA-Packet-8
| Heard | PPB | E % | M % | H % |
|---|---|---|---|---|
| 43 | 13.02 | 100% | 30% | 0% |
Conversion
| Team | Opponent | Part 1 | Part 2 | Part 3 | Total | Parts |
|---|---|---|---|---|---|---|
| Abbas I founded the Abbasids | UBC B | 0 | 0 | 10 | 10 | E |
| UBC A | The Unbearable Heaviness of History Players | 0 | 0 | 10 | 10 | E |
Summary
| Tournament | Edition | Match | Heard | PPB | E % | M % | H % |
|---|---|---|---|---|---|---|---|
| 2026 NAFTA at Stanford | 01/17/2026 | ✓ | 4 | 15.00 | 100% | 50% | 0% |
| 2026 NAFTA at UBC | 01/17/2026 | ✓ | 2 | 10.00 | 100% | 0% | 0% |
| 2025 NAFTA Online | 02/14/2026 | ✓ | 4 | 12.50 | 100% | 25% | 0% |
| 2026 NAFTA at Vanderbilt | 02/14/2026 | ✓ | 3 | 16.67 | 100% | 67% | 0% |
| 2025 NAFTA at Toronto | 09/13/2025 | ✓ | 5 | 10.00 | 100% | 0% | 0% |
| 2025 NAFTA at Maryland | 09/27/2025 | ✓ | 5 | 14.00 | 100% | 40% | 0% |
| 2025 NAFTA at Harvard | 10/04/2025 | ✓ | 3 | 13.33 | 100% | 33% | 0% |
| 2025 NAFTA at Oxford | 10/11/2025 | ✓ | 4 | 10.00 | 100% | 0% | 0% |
| 2025 NAFTA at Chicago | 11/08/2025 | ✓ | 6 | 11.67 | 100% | 17% | 0% |
| 2025 NAFTA at Columbia | 11/08/2025 | ✓ | 5 | 16.00 | 100% | 60% | 0% |
| 2025 NAFTA at Richmond | 12/20/2025 | ✓ | 2 | 15.00 | 100% | 50% | 0% |