Round 6: Tossup 19

In most cases, a structure involved in recruiting this molecule contains an internal loop, an apical loop with an AAR motif, and an AUGA quartet. While researching one moiety’s incorporation into clostridial glycine reductase, Thressa Stadtman’s group discovered this molecule. Iodo·thyronine deiodinase is a member of a protein family named for this molecule that includes thio·redoxin (15[1])reductase and gluta·thione peroxidase. Opal codons can only encode for this amino acid if the codon is directly upstream from a (*) SECIS (10[1])element. This amino acid and pyrrolysine are also known as the 21st and 22nd amino acids. This amino acid is derived by replacing the thiol sulfur of another amino acid (10[1])with a heavier chalcogen. For 10 points, what amino acid is the main biological form of selenium? ■END■

ANSWER: selenocysteine [or Sec or U; accept selenocysteine insertion sequence; prompt on selenoproteins; reject “cysteine” or “Cys” or “C”]
<KN, Chemistry> | NAFTA-Packet-6
= Average correct buzzpoint

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