Packet 11: Bonus 7

The SHOX gene is often stated to be able to “escape” this process. For 10 points each:
[10m] Name this epigenetic process that culminates in the formation of Barr bodies enriched with the macroH2A histone variant. This process is regulated by competing T·six and Xist (“exist”) long non-coding RNAs.
ANSWER: X-inactivation [or X-chromosome inactivation or lyonization; accept answers indicating one X chromosome is being inactivated; prompt on gene silencing; prompt on gene inactivation]
[10h] The SHOX gene can escape X-inactivation since its copies are located on these genetic regions. These telomeric regions found on X or Y chromosomes contain genes that do not fully exhibit sex linkage.
ANSWER: pseudoautosomal regions [or PARs; accept pseudoautosomal region 1 or PAR1; accept pseudoautosomal region 2 or PAR2]
[10e] Another pseudoautosomal gene, A·S·M·T, encodes for a methyl·transferase that converts N·A·S to this hormone. The pineal gland secretes this hormone to trigger the onset of sleep.
ANSWER: melatonin [reject “melanin”]
<KN, Biology> | NAFTA-Packet-11

HeardPPBE %M %H %
1217.50100%67%8%

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